GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs1930961 | 1 | rs6004655 | chr22:25855629 | CRYBB2 | chr22:25615612-25627836:+ | 1.09 | 7.13 | 1.92E-10 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004657 | chr22:25855714 | CRYBB2 | chr22:25615612-25627836:+ | 1.07 | 7.06 | 2.73E-10 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004658 | chr22:25856231 | CRYBB2 | chr22:25615612-25627836:+ | 1.09 | 7.04 | 2.94E-10 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004659 | chr22:25856411 | CRYBB2 | chr22:25615612-25627836:+ | 1.07 | 7.06 | 2.73E-10 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004662 | chr22:25862124 | CRYBB2 | chr22:25615612-25627836:+ | 1.09 | 7.11 | 2.16E-10 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004667 | chr22:25874464 | CRYBB2 | chr22:25615612-25627836:+ | -1.04 | -6.8 | 9.17E-10 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004668 | chr22:25874502 | CRYBB2 | chr22:25615612-25627836:+ | -1.1 | -7.33 | 7.64E-11 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004669 | chr22:25875803 | CRYBB2 | chr22:25615612-25627836:+ | 1.1 | 7.33 | 7.64E-11 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004671 | chr22:25879474 | CRYBB2 | chr22:25615612-25627836:+ | 1.12 | 7.51 | 3.14E-11 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004672 | chr22:25881013 | CRYBB2 | chr22:25615612-25627836:+ | 1.12 | 7.51 | 3.14E-11 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004673 | chr22:25885353 | CRYBB2 | chr22:25615612-25627836:+ | 1.03 | 6.92 | 5.32E-10 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs1930961 | 1 | rs6004675 | chr22:25889385 | CRYBB2 | chr22:25615612-25627836:+ | 1.08 | 7.35 | 6.97E-11 | Bipolar disorder with mood-incongruent psychosis |
| THYM | cis | rs60843830 | 1 | rs60149603 | chr2:285421 | SH3YL1 | chr2:218138-264810:- | -0.33 | -4.86 | 4.7E-6 | Spherical equivalent (joint main effects and education interaction) |
| THYM | cis | rs6911965 | 1 | rs60251819 | chr6:24468648 | GPLD1 | chr6:24428405-24489850:- | 0.45 | 4.67 | 9.97E-6 | Hematological and biochemical traits |
| THYM | cis | rs1499614 | 1 | rs60326618 | chr7:66166358 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Gout |